Stephanie Greene, MD

  • Professor
  • Vice Chair, Education
  • Director, Vascular Neurosurgery, UPMC Children's Hospital of Pittsburgh
  • Director, Perinatal Neurosurgery, UPMC Children's Hospital of Pittsburgh
  • Co-Director, Neurovascular Center of Excellence, UPMC Children’s Hospital of Pittsburgh
  • Director, Pediatric Neurosurgery Fellowship
  • Site Program Director, CHP Neurosurgery Residency Program

Stephanie Greene, MD, is a nationally recognized expert in pediatric vascular neurosurgery and congenital neurosurgical disorders. She joined the faculty of the Department of Neurological Surgery in the pediatric neurosurgery division at UPMC Children’s Hospital of Pittsburgh in 2009. She was the director of pediatric neurosurgery at Hasbro Children’s Hospital, affiliated with Brown University, prior to accepting her position at UPMC Children’s Hospital of Pittsburgh. She is the director of vascular neurosurgery and perinatal neurosurgery, and the co-director of the newly established Neurovascular Center of Excellence at UPMC Children’s Hospital of Pittsburgh.

Dr. Greene graduated from Dartmouth College in 1993 with a degree in biology and psychology, and a concentration in neuroscience. She earned her medical degree from Albany Medical College, and completed her neurosurgical residency at Harvard University in the Brigham & Women’s and Children’s Hospital Boston program. Dr. Greene received additional subspecialty fellowship training in pediatric neurosurgery through the University of Washington at Seattle Children’s Hospital in 2005. She is board certified in both adult and pediatric neurosurgery. She is a fellow of the American Association of Neurological Surgeons, and a member of the Congress of Neurological Surgeons and American Society of Pediatric Neurosurgeons. She is on the editorial board of the Journal of Neurosurgery: Pediatrics, and a regular guest examiner for the American Board of Neurological Surgeons. Her research focuses on the development of fetal neurosurgical technology, as well as on the clinical outcomes of a variety of pediatric neurosurgical conditions.

Dr. Greene's publications can be reviewed through the National Library of Medicine's publication database.

Specialized Areas of Interest

Arteriovenous malformation, moyamoya syndrome, cavernous malformation, Chiari malformation, myelomeningocele, congenital spinal dysraphism, brain tumor, fetal neurosurgery, peripheral nerve disorder.

Board Certifications

American Board of Neurological Surgery
American Board of Pediatric Neurological Surgery

Hospital Privileges

UPMC Children's Hospital of Pittsburgh
UPMC Magee-Womens Hospital

Professional Organization Membership

American Association of Neurological Surgeons
American Society of Pediatric Neurosurgeons
AANS/CNS Joint Section on Pediatric Neurosurgery
Congress of Neurological Surgeons
Women in Neurosurgery

Professional Activities

Editorial Board, Journal of Neurosurgery: Pediatrics
Resident Mentorship Program, American Association of Neurological Surgeons
Resident Mentorship Program, Women in Neurosurgery Resident Mentorship Program
CNS/AANS Joint Section on Pediatric Neurosurgery Executive Committee
Co-chair, Traveling Fellowship Subcommittee/Education Committee, Joint Section on Pediatric Neurosurgery
Steering Committee, North American Fetal Treatment Network
Oral Board Guest Examiner, American Board of Neurological Surgeons
Coordinating Committee, National Spina Bifida Patient Registry

Education & Training

  • AB, Biology/Psychology, Dartmouth College, 1993
  • MD, Albany Medical College, 1998
  • Residency, Neurological Surgery, Penn State University, 2000
  • Residency, Neurological Surgery, Harvard University, 2004
  • Fellowship, Pediatric Neurological Surgery, 2005

Honors & Awards

  • Pittsburgh’s Best Doctors, Pittsburgh Magazine, 2021-23
  • Castle Connolly Top Doctor, 2016-present
  • Marquis Who’s Who in the World, 2018-present
  • Marquis Who’s Who in America, 2018-present
  • Castle Connolly Exceptional Women in Medicine, 2017-present
  • American’s Most Honored Professionals (American Registry), 2017-present
  • Castle Connolly Regional Top Doctor, 2017-present
  • Castle Connolly Metro Area Top Doctor, 2016-present
  • Top Ten Doctor – Metro Area, City, and State (Vitals.com), 2013-present
  • Patients’ Choice 5-Year Honoree, 2013-present
  • America’s Most Compassionate Doctors, 2011-present
  • Cambridge’s Who’s Who 2011 America’s Top Surgeons, 2007, 2011, 2012
  • Patients’ Choice Award, 2008-present

Research Activities

Dr. Greene collaborates on translational research with a team developing a ventriculoamniotic shunt to treat fetal aqueductal stenosis. The team has obtained two patents, and published multiple studies on the topic. The study is moving toward an application to the Federal Drug Administration for a Humanitarian Use Device exemption allowing for compassionate use in humans. 

Dr. Greene is the site principal investigator in multi-institutional prospective clinical studies on Chiari I malformation, moyamoya syndrome, myelomeningocele and aqueductal stenosis. 

As the co-director of the newly formed Neurovascular Center of Excellence at UPMC Children’s Hospital of Pittsburgh, Dr. Greene is developing a biorepository of tissue samples for future laboratory investigations.

Dr. Greene’s clinical interests have generated projects analyzing outcomes of arteriovenous malformations, cavernous malformations, moyamoya syndrome, myelomeningocele, tethered cord syndrome, Chiari I and II malformation, and the neurosurgical aspects of various genetic syndrome.

Media Appearances

UPMC Bridging the Great Health Divide: UMPC Neurovascular Center of Excellence
May 11, 2023
WDTV-5 (Bridgeport, W.Va.)

Exploring the Ever-Advancing Field of Pediatric Neurosurgery with Dr. Stephanie Greene
March 21, 2023
That's Pediatrics Podcast

UPMC doctors perform life changing surgery to repair spinal defect
June 10, 2019
Lock Haven Express

In-utero Fetal Surgery Carried For the First Time Ever In Pittsburgh
June 10, 2019
Gobal Market News 24

Pitt Researchers Perform University’s First In Utero Spina Bifida Surgery
June 5, 2019
PittWire

Pittsburgh Surgeons Repair Spina Bifida in Utero at 25 Weeks Gestation
June 5, 2019
Christian News

Doctors Operate on Baby Still in Mother's Womb
June 4, 2019
CNN/HLN Morning Express with Robin Meade

How Womb Surgery Saved A Baby From Being Born With A Birth Defect
June 4, 2019
medicaldaily.com

Breakthrough in-utero surgery treats ‘devastating’ birth defect
June 3, 2019
New York Post

First-ever in-utero surgery to treat spina bifida
June 3, 2019
medicalxpress.com

Thanks to surgery in the womb, newborn avoids devastating birth defect
June 2, 2019
WCTV-TV, Tallahassee, Fla.

Pittsburgh surgeons say results are good in their first spina bifida repair before baby is born
May 31, 2019
Pittsburgh Post-Gazette

Pittsburgh doctors perform first-of-its-kind in-utero fetal surgery to repair spina bifida
May 30, 2019
WTAE-TV

From the operating room to the pitcher's mound
April 19, 2019
WTAE-TV

Mt. Pleasant girl overcomes effects of brain surgery
March 5, 2014
Pittsburgh Tribune-Review

ADHD May Be Tied to Longer-Lasting Head Injury
June 25, 2013
U.S. News & World Report Health Day

UPMC Videos & Patient Stories

Surgical Treatment of Moyamoya in the Pediatric Population
Dr. Greene explains how surgical intervention is the only viable treatment to effectively halt neurological decline associated with moyamoya.

Brain Care Institute Patient Story: Nathan’s Story
See how one family found help for moyamoya through the expertise of Dr. Greene of the Brain Care Institute.